1615710-98-9Relevant academic research and scientific papers
An approach for disaccharide chiron synthesis using a Ferrier-type rearrangement
Komor, Katarzyna,Szeja, Wies?aw,Bieg, Tadeusz,Ku?nik, Nikodem,Pastuch-Gawo?ek, Gabriela,Komor, Roman
, p. 3709 - 3712 (2014)
We report a new approach for the synthesis of new chiral synthons in which two unsaturated sugars are linked via a glycosidic bond. The di-unsaturated disaccharide can be further functionalized using effective, highly selective methods and used in convergent syntheses of relatively complex glycoconjugates. Our approach utilizes in situ generation of active glycosyl donors via Ferrier-type rearrangement under phase-transfer conditions and subsequent reaction with a nucleophile.
