1616063-07-0

Upstream product

• 1616062-92-0 (E)-2,2-dimethoxy-6,10-dimethylundec-5-ene 
• 149075-51-4 (E)-10,10-dimethoxy-2,6-dimethylundeca-2,6-diene 
• 3796-70-1 trans geranyl acetone 
• 17949-01-8 (Z)-6,10-dimethylundec-5-en-2-one 
• 1616062-93-1 (Z)-2,2-dimethoxy-6,10-dimethylundec-5-ene 
• 1616062-91-9 (Z)-10,10-dimethoxy-2,6-dimethylundeca-2,6-diene 

Downstream Products

• 3625-46-5 (7R)-3,7,11-trimethyldodec-1-en-3-ol 
• 1604-35-9 (7R)-3,7,11-trimethyldodec-1-yn-3-ol 

Relevant academic research and scientific papers

USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINED ASYMMETRIC HYDROGENATIONS

The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves two asymmetric hydrogenation steps. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.

USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINING ASYMMETRIC HYDROGENATION AND ISOMERIZATION

The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves an asymmetric hydrogenation and an isomerization step. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.

PROCESS OF ASYMMETRIC HYDROGENATION OF KETALS AND ACETALS

The present invention relates to a process of the asymmetric hydrogenation of a ketal of an unsaturated ketone or an acetal of an unsaturated aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex. This process yields chiral compounds in a very efficient way and is very advantageous in that the amount of iridium complex can be remarkably reduced.

(6R,10R)-6,10,14-TRIMETYLPENTADECAN-2-ONE PREPARED FROM 6,10-DIMETYLUNDEC-5-EN-2-ONE OR 6,10-DIMETYLUNDECA-5,9-DIEN-2-ONE

The present invention relates to a process of manufacturing (6R,10R)-6,10,14-trimetylpentadecan-2-one in a multistep synthesis from 6,10-dimetylundec-5-en-2-one or 6,10-dimetylundeca-5,9-dien-2-one. The process is very advantageous in that it forms in an efficient way the desired chiral product from a mixture of stereoisomers of the starting product.