161610-09-9

Basic information

• Product Name: 4-(4'-N-METHYLBENZAMIDE)PIPERIDINE
• Synonyms: 4-(4-Methylaminocarbonylphenyl)piperidine;Benzamide, N-methyl-4-(4-piperidinyl)-;N-methyl-4-(piperidin-4-yl)benzamide hydrochloride
• CAS NO: 161610-09-9
• Molecular Formula: C₁₃H₁₈N₂O
• Molecular Weight: 218.29
• Mol File: 161610-09-9.mol

Chemical Properties

• Boiling Point: 399.847 °C at 760 mmHg
• Flash Point: 160.596 °C
• Appearance: /
• Density: 1.054
• PKA: 15.15±0.46(Predicted)
• CAS DataBase Reference: 4-(4'-N-METHYLBENZAMIDE)PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4'-N-METHYLBENZAMIDE)PIPERIDINE(161610-09-9)
• EPA Substance Registry System: 4-(4'-N-METHYLBENZAMIDE)PIPERIDINE(161610-09-9)

Safety Data

• Hazardous Substances Data: 161610-09-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
4-(4'-N-METHYLBENZAMIDE)PIPERIDINE is used as a key intermediate in the synthesis of various pharmaceuticals, particularly for the development of antipsychotic and analgesic drugs. Its unique structure allows for the creation of compounds that can effectively target specific receptors in the brain, offering potential therapeutic benefits for patients.
Used in Neuroscience and Drug Discovery:
In the field of neuroscience, 4-(4'-N-METHYLBENZAMIDE)PIPERIDINE has shown potential as an inhibitor of neurotransmitter receptors in the brain. This property makes it a valuable compound for the study of brain function and the development of new drugs to treat neurological disorders.
Used in Anti-Inflammatory and Antioxidant Applications:
4-(4'-N-methylbenzamido)piperidine has demonstrated anti-inflammatory and antioxidant properties, making it a promising candidate for the development of new medications to treat inflammatory conditions and oxidative stress-related diseases. Its ability to modulate inflammatory responses and protect cells from oxidative damage could lead to innovative treatments in the medical field.

Upstream product

• 100-68-5 methyl-phenyl-thioether 

Relevant articles and documents

Aryl substituted heterocycles

The present invention concerns the novel use of aryl substituted heterocycles of formula I, set out below, which antagonize the pharmacological actions of one of ent endogenous neuropeptide tachykinins an the neurokinin 2 (NK2) receptor making them useful whenever such antagonism is desired, such as in the treatment of asthma and related conditions. The invention also provides pharmaceutical compositions containing the aryl substituted heterocycles for use in such treatment. Certain novel aryl substituted heterocycles of formula I and novel intermediates for their manufacture are also provided. STR1