161611-29-6Relevant articles and documents
Discovery of High-Affinity Inhibitors of the BPTF Bromodomain
Lu, Tian,Lu, Haibo,Duan, Zhe,Wang, Jun,Han, Jie,Xiao, Senhao,Chen, HuanHuan,Jiang, Hao,Chen, Yu,Yang, Feng,Li, Qi,Chen, Dongying,Lin, Jin,Li, Bo,Jiang, Hualiang,Chen, Kaixian,Lu, Wenchao,Lin, Hua,Luo, Cheng
, p. 12075 - 12088 (2021)
The dysfunctional bromodomain PHD finger transcription factor (BPTF) exerts a pivotal influence in the occurrence and development of many human diseases, particularly cancers. Herein, through the structural decomposition of the reported BPTF inhibitor TP-
2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety
-
Page/Page column 13, (2010/02/06)
This invention is directed to pyrimidine derivatives which are selective antagonists for the GalR3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceuti