16162-59-7

Upstream product

• 150-78-7 1,4-dimethoxybezene 
• 7417-19-8 2-(2,5-dimethoxyphenyl)ethanol 
• 74-88-4 methyl iodide 

Downstream Products

• 121649-10-3 (+/-)-1-<2,5-Dimethoxy-4-(2-tosyloxyethyl)phenyl>-2-trifluoroacetamidopropane 
• 121649-07-8 (+/-)-1-<2,5-Dimethoxy-4-(2-fluoroethyl)phenyl>-2-trifluoroacetamidopropane 
• 121649-06-7 (+/-)-1-<2,5-Dimethoxy-4-(2-hydroxyethyl)phenyl>-2-trifluoroacetamidopropane 
• 121649-08-9 (+/-)-1-<2,5-Dimethoxy-4-(ethen)phenyl>-2-trifluoroacetamidopropane 
• 121649-03-4 1,4-Dimethoxy-2-(2-methoxy-ethyl)-5-((E)-2-nitro-propenyl)-benzene 
• 121649-04-5 2-[4-(2-Amino-propyl)-2,5-dimethoxy-phenyl]-ethanol 
• 121649-01-2 4-(2-Fluoroethyl)-2,5-dimethoxyamphetamine 
• 121649-02-3 2,5-Dimethoxy-4-(2-methoxy-ethyl)-benzaldehyde 

Relevant academic research and scientific papers

Preparation of vinyl ethers using a Wittig approach, and their subsequent hydrogenation employing continuous-flow processing

A methodology is reported for the preparation of various aromatic-functionalized vinyl ethers using a Wittig approach. The subsequent hydrogenation of the vinyl ether products to their saturated analogs is also performed and is streamlined by employing continuous-flow processing.

SYNTHESIS OF 1--2-AMINOPROPANE: STUDIES RELATED TO (18)F-LABELED SEROTONIN RECEPTOR LIGANDS

Synthesis of the titled 2,5-dimethoxy-4-fluoroalkylamphetamine is reported.The highly functionalized aromatic nucleus of the key fluorination precursor was utimately derived from a low temperature aromatic halogen-lithium exchange reaction followed by alkylation of the resultant anion with ethylene oxide.