1616246-67-3Relevant academic research and scientific papers
Visible-light-promoted redox neutral C-H amidation of heteroarenes with hydroxylamine derivatives
Qin, Qixue,Yu, Shouyun
supporting information, p. 3504 - 3507 (2014/07/21)
A room temperature redox neutral direct C-H amidation of heteroarenes has been achieved. Hydroxylamine derivatives, which are easily accessed, have been employed as tunable nitrogen sources. These reactions were enabled by a visible-light-promoted single-electron transfer pathway without a directing group. A variety of heteroarenes, such as indoles, pyrroles, and furans, could go through this amidation with high yields (up to 98%). These reactions are highly regioselective, and all the products were isolated as a single regioisomer.
