1616356-75-2Relevant academic research and scientific papers
Anti-markovnikov hydroamination of alkenes catalyzed by a two-component organic photoredox system: Direct access to phenethylamine derivatives
Nguyen, Tien M.,Manohar, Namita,Nicewicz, David A.
supporting information, p. 6198 - 6201 (2014/06/23)
Disclosed herein is a general catalytic system for the intermolecular anti-Markovnikov hydroamination of alkenes. By using an organocatalytic photoredox system, α- and β-substituted styrenes as well as aliphatic alkenes undergo anti-Markovnikov hydroamination. Heterocyclic amines were also successfully employed as nitrogen nucleophiles, thus providing a direct route to heterocyclic motifs common in medicinal agents.
