1616493-84-5

Basic information

• Product Name: C₂₁H₂₃BrFNO₂S
• Synonyms: C₂₁H₂₃BrFNO₂S
• CAS NO: 1616493-84-5
• Molecular Weight: 452.388
• Mol File: 1616493-84-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₃BrFNO₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₃BrFNO₂S(1616493-84-5)
• EPA Substance Registry System: C₂₁H₂₃BrFNO₂S(1616493-84-5)

Safety Data

• Hazardous Substances Data: 1616493-84-5(Hazardous Substances Data)

Upstream product

• 1481-32-9 6-fluoroindan-1-one 
• 1039750-63-4 (S,E)-N-(1-(4-bromophenyl)ethylidene)-2-methylpropane-2-sulfinamide 

Relevant articles and documents

Highly efficient and generalized asymmetric synthesis of quaternary stereogenic carbon-containing β-amino indanones/indanoles via Mannich-type additions between 1-indanones and N-tert-butanesulfinylketimines

Here we report that, unlike other ketones, 1-indanone and acetophenone derived enolates undergo Mannich-type addition reactions with N-tert-butanesulfinyl ketimines with excellent yields (up to 98%) and diastereoselectivity (>99/1). The resulting compounds represent a new type of biologically relevant β-aminoketone derivative bearing quaternary stereogenic carbon, which could be further converted into the corresponding β-amino ketones and β-amino alcohols, possessing three consecutive stereogenic centres. This journal is