16166-22-6Relevant articles and documents
Substituted pyrimidine compositions and methods of use
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, (2008/06/13)
Substituted pyrimidines that have the general structure: in which the symbol R1represents a C1-C6alkyl, C1-C6alkoxy or halogen atom; R2represents a phenyl group, substituted phenyl group, benzyl moiety, substituted benzyl moiety, C3-C7cycloalkyl, or substituted C3-C7cycloalkyl; R3represents a hydrogen or C1-C6alkyl group, R4represents —H, —OH, —N3or —NHCOCH3; and R5represents H are provided. These compounds have activity as inhibitors of phospholipase A2, and are useful in treating disorders mediated by phospholipase A2.