1616635-05-2

Basic information

• Product Name: 1-allyl-3-bromo-2-(3-methoxyphenyl)-2,1-borazaronaphthalene
• Synonyms: 1-allyl-3-bromo-2-(3-methoxyphenyl)-2,1-borazaronaphthalene
• CAS NO: 1616635-05-2
• Molecular Weight: 354.054
• Mol File: 1616635-05-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-allyl-3-bromo-2-(3-methoxyphenyl)-2,1-borazaronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-allyl-3-bromo-2-(3-methoxyphenyl)-2,1-borazaronaphthalene(1616635-05-2)
• EPA Substance Registry System: 1-allyl-3-bromo-2-(3-methoxyphenyl)-2,1-borazaronaphthalene(1616635-05-2)

Safety Data

• Hazardous Substances Data: 1616635-05-2(Hazardous Substances Data)

Upstream product

• 1616634-86-6 1-allyl-2-(3-methoxyphenyl)-2,1-borazaronaphthalene 
• 1510778-95-6 allyl(2-vinylphenyl)amine 

Relevant articles and documents

Accessing molecularly complex azaborines: Palladium-catalyzed Suzuki-Miyaura cross-couplings of brominated 2,1-borazaronaphthalenes and potassium organotrifluoroborates

Despite their potential applications in both medicinal chemistry and materials science, there have been limited reports on the functionalization of 2,1-borazaronaphthalenes since their discovery in 1959. To access new chemical space and build molecular complexity, the Suzuki-Miyaura cross-coupling of brominated 2,1-borazaronaphthalenes has been investigated. The palladium-catalyzed cross-coupling proceeds with an array of potassium (hetero)aryltrifluoroborates in high yield with low catalyst loadings under mild reaction conditions. By the use of a high-yielding bromination of various 2,1-borazaronaphthalenes to generate electrophilic azaborine species, a library of 3-(hetero)aryl and 3,6-diaryl-2,1-borazaronaphthalenes has been synthesized.