1616666-51-3

Basic information

• Product Name: N-(2-(2-bromobenzylthio)-2-phenylethyl)-4-methylbenzenesulfonamide
• Synonyms: N-(2-(2-bromobenzylthio)-2-phenylethyl)-4-methylbenzenesulfonamide
• CAS NO: 1616666-51-3
• Molecular Weight: 476.458
• Mol File: 1616666-51-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-(2-bromobenzylthio)-2-phenylethyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(2-bromobenzylthio)-2-phenylethyl)-4-methylbenzenesulfonamide(1616666-51-3)
• EPA Substance Registry System: N-(2-(2-bromobenzylthio)-2-phenylethyl)-4-methylbenzenesulfonamide(1616666-51-3)

Safety Data

• Hazardous Substances Data: 1616666-51-3(Hazardous Substances Data)

Upstream product

• 143888-85-1 (2-bromophenyl)methanethiol 
• 24395-14-0 N-(p-tolylsulfonyl)-2-phenylaziridine 

Downstream Products

• 1616666-53-5 3-phenyl-1-tosyl-1,2,3,5-tetrahydrobenzo[e][1,4]thiazepine 

Relevant articles and documents

Syntheses of imidazo-, oxa-, and thiazepine ring systems via ring-opening of aziridines/Cu-catalyzed C-N/C-C bond formation

A simple and unpredicted synthetic pathway toward racemic and scalemic tetrahydrodibenzoimidazoazepines has been invented serendipitously proceeding through an SN2-type ring-opening of N-activated aziridines with 2-bromobenzylamine followed by a hitherto unprecedented cascade cyclization reaction sequence comprising a Cu-catalyzed cross dehydrogenation C-N coupling and an Ullmann C-C bond formation reaction. The tetrahydrobenzoxazepine and the tetrahydrobenzothiazepine derivatives have also been synthesized via the ring-opening of aziridines with 2-bromobenzyl alcohols and -mercaptan, respectively, followed by Cu-catalyzed N-arylation reaction.