1616736-15-2Relevant academic research and scientific papers
Synthesis of fully functionalized iminolactones via an isocyanide-based three-component reaction
Shaabani, Ahmad,Mahyari, Mojtaba,Hajishaabanha, Fatemeh,Mofakham, Hamid
, p. 1183 - 1187 (2014)
An efficient method has been developed for the one-pot synthesis of fully functionalized iminolactones containing pyran-furan moiety. The zwitterion formed from an alkyl or an aryl isocyanide and a dialkyl acetylenedicarboxylate reacts with 3-acetyl-6-methyl-3H-pyran-2,4-dione to form 2,5-dihydro-2-(3,4- dihydro-6-methyl-2,4-dioxo-2H-pyran-3-yl)-2-methyl-5-(methylimino)furan-3, 4-dicarboxylates in relatively good yields at room temperature without using any catalyst.
