161674-83-5Relevant academic research and scientific papers
Synthesis and structure-activity relationship of (lactamylvinyl)cephalosporins exhibiting activity against staphylococci, pneumococci, and enterococci
Heinze-Krauss, Ingrid,Angehrn, Peter,Guerry, Philippe,Hebeisen, Paul,Hubschwerlen, Christian,Kompis, Ivan,Page, Malcolm G. P.,Richter, Hans G. F.,Runtz, Valérie,Stalder, Henri,Weiss, Urs,Wei, Chung-Chen
, p. 1864 - 1871 (2007/10/03)
The synthesis and structure-activity relationships of a new class of vinylcephalosporins substituted with a lactamyl residue (1) are described. These compounds show excellent activity against enterococci and retain the broad spectrum activity of third-gen
Cephalosporin antibiotics
-
, (2008/06/13)
The present invention relates to compounds of the formula STR1 wherein R1 is an acyl group derived from a carboxylic acid, hydrogen, or an amino protecting group; R2 is hydrogen, hydroxy, lower alkyl-Qp -, cycloalkyl, lowe
