1616788-07-8

Basic information

• Product Name: 5-methyl-2-(3-phenylprop-2-yn-1-yl)isoindoline
• Synonyms: 5-methyl-2-(3-phenylprop-2-yn-1-yl)isoindoline
• CAS NO: 1616788-07-8
• Molecular Weight: 247.34
• Mol File: 1616788-07-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-methyl-2-(3-phenylprop-2-yn-1-yl)isoindoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-2-(3-phenylprop-2-yn-1-yl)isoindoline(1616788-07-8)
• EPA Substance Registry System: 5-methyl-2-(3-phenylprop-2-yn-1-yl)isoindoline(1616788-07-8)

Safety Data

• Hazardous Substances Data: 1616788-07-8(Hazardous Substances Data)

Upstream product

• 164732-09-6 4-methyl-1,2-bis(bromomethyl)benzene 
• 591-50-4 iodobenzene 
• 1616787-83-7 C₁₂H₁₃N 

Relevant articles and documents

Gold-catalyzed [1,5]-hydride shift onto unactivated alkynes to trigger an intermolecular Diels-Alder reaction

A [1,5]-hydride shift of sp3 C-H onto an unactivated carbon-carbon triple bond catalyzed by a gold(I) complex enabled N-propargylisoindolines to be latent dienes and therefore triggered an intermolecular Diels-Alder reaction with dienophiles. This protocol provides an atom-economical and straightforward approach to access a wide range of polycyclic skeletons in high yields and with excellent diastereoselectivities from easily accessible molecules.