1616919-23-3Relevant academic research and scientific papers
N-heterocyclic carbene/Lewis acid strategy for the stereoselective synthesis of spirocyclic oxindole-dihydropyranones
Xiao, Zhaoxin,Yu, Chenxia,Li, Tuanjie,Wang, Xiang-Shan,Yao, Changsheng
, p. 3632 - 3635 (2014)
Under the cooperative catalysis of NHC/Lewis acid, the mild, straightforward [4 + 2] annulation of α-bromo-α,β-unsaturated aldehydes bearing γ-H with isatin derivatives gave spirocyclic oxindole-dihydropyranones stereoselectively. This approach is particu
