1616959-76-2

Upstream product

• 1214347-63-3 C₁₂H₈F₃N 
• 67567-26-4 4-bromo-2,6-difluoroaniline 
• 768-35-4 3-fluorophenylboronic acid 
• 709024-30-6 6-ethoxy-4-hydroxy-3-methyl-quinoline-2-carboxylic acid 
• 62776-06-1 6-ethoxy-4-hydroxy-3-methyl-quinoline-2-carboxylic acid ethyl ester 
• 759-65-9 diethyl oxalpropionate 
• 156-43-4 4-Ethoxyaniline 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 1616959-67-1 6-ethoxy-4-hydroxy-3-methyl-N-(3,3',5-trifluorobiphenyl-4-yl)quinoline-2-carboxamide 

Downstream Products

• 1616959-85-3 C₂₆H₁₈F₃N₃O₂ 
• 1616959-45-5 6-ethoxy-3-methyl-2-[(3,3',5-trifluorobiphenyl-4-yl)carbamoyl]quinoline-4-carboxylic acid 

Relevant academic research and scientific papers

Design, synthesis and pharmacological evaluation of novel substituted quinoline-2-carboxamide derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents

In continuation of our research for novel human dihydroorotate dehydrogenase (hDHODH) inhibitors, herein we reported design, synthesis and pharmacological evaluation of novel substituted quinoline-2-carboxamide derivatives. Human DHODH enzyme inhibition a