1616969-91-5Relevant academic research and scientific papers
Small-molecule inhibitors of AF6 PDZ-mediated protein-protein interactions
Vargas, Carolyn,Radziwill, Gerald,Krause, Gerd,Diehl, Anne,Keller, Sandro,Kamdem, Nestor,Czekelius, Constantin,Kreuchwig, Annika,Schmieder, Peter,Doyle, Declan,Moelling, Karin,Hagen, Volker,Schade, Markus,Oschkinat, Hartmut
, p. 1458 - 1462 (2014)
PDZ (PSD-95, Dlg, ZO-1) domains are ubiquitous interaction modules that are involved in many cellular signal transduction pathways. Interference with PDZ-mediated protein-protein interactions has important implications in disease-related signaling process
