161726-04-1Relevant articles and documents
Synthesis of (+)-methyl (R,E)-6-benzyloxy-4-hydroxy-2-hexenoate and its mesylate derivative
De March,Figueredo,Font,Monsalvatje
, p. 331 - 342 (1995)
Methyl (E)-6-benzyloxy-4-hydroxy-2-hexenoate is prepared in both racemic and enantiopure form through reaction between (2-benzyloxy)ethyloxirane and the dianion of phenylselenoacetic acid followed by esterification with diazomethane, oxidation to the selenoxide and subsequent pyrolysis in 72% overall yield.