1617498-45-9Relevant academic research and scientific papers
REACTIVE LABELLING COMPOUNDS AND USES THEREOF
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Paragraph 00156; 00161; 00167, (2015/12/08)
Provided are azido-BODIPY compounds of formula (I), cyclooctyne-based fluorogenic probes of formula (IV), and activity-based probes of formula (VI). These compounds undergo azide-alkyne cycloadditions (AAC) with to form triazolyl products. The provided compounds are useful for detection and imaging of alkyne-, or azide-containing molecules. Methods for detection and imaging biomolecules using compounds of the present disclosure are disclosed.
An azido-BODIPY probe for glycosylation: Initiation of strong fluorescence upon triazole formation
Shie, Jiun-Jie,Liu, Ying-Chih,Lee, Yu-Ming,Lim, Carmay,Fang, Jim-Min,Wong, Chi-Huey
, p. 9953 - 9961 (2014/08/05)
We have designed a low fluorescent azido-BODIPY-based probe AzBOCEt (Az10) that undergoes copper(I)-catalyzed 1,3-dipolar cycloadditions with alkynes to yield strongly fluorescent triazole derivatives. The fluorescent quantum yield of a triazole product T
