161754-60-5 Usage
General Description
"(S)-N-(2,2-DIFLUOROETHYLIDENE)-1-PHENYLETHYLAMINE" is a chemical compound with the molecular formula C10H12F2N. It is a chiral amine with a difluoroethylidene substituent attached to a phenylethylamine backbone. (S)-N-(2,2-DIFLUOROETHYLIDENE)-1-PHENYLETHYLAMINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its unique structure and properties make it suitable for use in various chemical reactions and transformations, making it a valuable building block in organic synthesis. Its potential applications include the development of new drugs, pesticides, and other important compounds in the fields of medicine and agriculture.
Check Digit Verification of cas no
The CAS Registry Mumber 161754-60-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,7,5 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 161754-60:
(8*1)+(7*6)+(6*1)+(5*7)+(4*5)+(3*4)+(2*6)+(1*0)=135
135 % 10 = 5
So 161754-60-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H11F2N/c1-8(13-7-10(11)12)9-5-3-2-4-6-9/h2-8,10H,1H3/b13-7+/t8-/m0/s1
161754-60-5Relevant articles and documents
Highly diastereo- and enantioselective vinylogous Mannich reactions of fluorinated aldimines with siloxyfurans
Zhao, Qian-Yi,Yuan, Zhi-Liang,Shia, Min
supporting information; experimental part, p. 637 - 643 (2011/04/25)
A highly regio- and enantioselective asymmetric vinylogous Mannich reaction of readily available fluorinated aldimines bearing a chiral auxiliary [(S)-1-phenylethyl group] with siloxyfurans to afford chiral fluorine-containing γ-butenolide or γ-lactone derivatives has been developed in the presence of silver acetate (10 mol%) and axially chiral phosphine-oxazoline ligand L1 (11 mol%). In most cases, the corresponding fluorinated adducts were obtained in high yields, good to excellent enantiomeric excesses and up to > 20:1 dr.
