161772-82-3Relevant articles and documents
Palladium-catalyzed heck reaction of aryl chlorides under mild conditions promoted by organic ionic bases
Xu, Hua-Jian,Zhao, Yong-Qiang,Zhou, Xin-Feng
experimental part, p. 8036 - 8041 (2011/12/02)
An efficient Pd-catalyzed Heck reaction of aryl chlorides with olefins under mild conditions is described. High yields of products were achieved with n-Bu4N+OAc- as base. Significantly, the temperature of the Heck reaction of diverse nonactivated aryl chlorides can be lowered to 80 °C. The new reaction system can also tolerate a wider range of olefins.
Applications of a monomeric orthopalladate complex containing mixed phosphorus-nitrogen donors in the Heck reaction
Hajipour, Abdol Reza,Rafiee, Fatemeh,Rouho, Arnold E.
experimental part, p. 4782 - 4787 (2011/10/04)
The [Pd{C6H2(CH2CH2NH 2)-(OMe)2,3,4}Br(PPh3)] monomeric orthopalladate complex of homoveratrylamine and triphenylphosphine was synthesized and its application in Heck coupling reactions was investigated. This complex had been demonstrated to be more active than the corresponding dimeric catalyst for Heck reactions of aryl iodides, bromides and even chlorides and also arenesulfonyl chlorides. The cross-coupled products were produced in excellent yields using catalytic amounts of [Pd{C6H 2(CH2CH2NH2)-(OMe) 2,3,4}Br(PPh3)] as a thermally stable and oxygen insensitive complex in NMP at 130 °C.
Biopolymer-metal complex wool-Pd as a highly active heterogeneous catalyst for Heck reaction in aqueous media
Wu, Shang,Ma, Hengchang,Jia, Xiaojie,Zhong, Yunmei,Lei, Ziqiang
experimental part, p. 250 - 256 (2011/02/27)
Heterogeneous palladium catalysts, a biopolymer complex wool-Pd, have been applied in water-mediated coupling reactions of aryl bromides without assistance of any phosphine ligands. The catalyst was characterized by XPS, ICP. The results showed that aryl bromides could carry out the coupling reaction with a variety of alkenes at 80 °C, in aqueous media under atmospheric condition. More importantly, the cheap catalyst is stable, which shows negligible metal leaching, and retain good activity for at least ten successive runs without any additional activation treatment. This approach would be very useful from a practical viewpoint.
A novel approach to the synthesis of benzoic and cinnamic acid derivatives with nor-isoprenoid substituents
Kryshtal, G. V.,Zhdankina, G. M.,Serebryakov, E. P.
, p. 866 - 869 (2007/10/02)
A novel strategy for the synthesis of 4-(nor-polyprenyl)-substituted benzoic acids and their esters of the general formula 1 as well as their vinylogs of the type 2, based on the use of terephthalic aldehyde (3) and its tetramethyl acetal (13), is elaborated.The carbonyl groups in dialdehydes 3 and 12 can be selectively involved in the reaction sequences leading to the introduction of both aliphatic and functional substituents in positions 1 and 4 of the benzene ring.
