161832-74-2 Usage
Uses
Used in Pharmaceutical Synthesis:
(R)-(+)-2-AMINO-4-METHYL-1,1-DIPHENYL-1-PENTANOL is used as a key intermediate in the synthesis of various pharmaceuticals for its unique molecular structure and chiral properties, contributing to the development of new drugs with enhanced efficacy and selectivity.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (R)-(+)-2-AMINO-4-METHYL-1,1-DIPHENYL-1-PENTANOL is used as a chiral building block for the design and synthesis of novel bioactive molecules, targeting specific biological pathways and receptors with improved pharmacological profiles.
Used in Drug Development:
(R)-(+)-2-AMINO-4-METHYL-1,1-DIPHENYL-1-PENTANOL is employed in drug development as a chiral template to create enantiomerically pure compounds, which can exhibit different biological activities and reduce potential side effects associated with racemic mixtures.
Further research and studies are being conducted to explore the potential uses of (R)-(+)-2-AMINO-4-METHYL-1,1-DIPHENYL-1-PENTANOL in the field of medicine, with a focus on its applications in drug design and the development of innovative therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 161832-74-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,8,3 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 161832-74:
(8*1)+(7*6)+(6*1)+(5*8)+(4*3)+(3*2)+(2*7)+(1*4)=132
132 % 10 = 2
So 161832-74-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H23NO/c1-14(2)13-17(19)18(20,15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,14,17,20H,13,19H2,1-2H3/t17-/m1/s1
161832-74-2Relevant academic research and scientific papers
Large-scale synthesis of Singh's catalyst in a one-pot procedure starting from proline
Berkessel, Albrecht,Harnying, Wacharee,Duangdee, Nongnaphat,Neudoerfl, Joerg-M.,Groeger, Harald
, p. 123 - 128 (2012/05/20)
A practical one-pot procedure for the preparation of Singh's catalyst from either l-/d-proline or Boc-proline is described. The coupling partner, a chiral amino alcohol, can be prepared and used directly without purification from the corresponding amino acid ester. Moreover, a procedure for tert-butoxycarbonyl (Boc) group removal using concentrated HCl in MeOH-DCM was developed and utilized for the multigram-scale synthesis of Singh's catalyst.
Easy preparation of enantiopure C2-symmetrical aminoalcohols derived from m-xylylene diamine
Andres,Martinez,Pedrosa,Perez-Encabo
, p. 57 - 66 (2007/10/02)
The title compounds were prepared by condensation of isophthaldehyde with chiral amino alcohols or α-amino esters in three different ways depending on the substitution pattern. These methods are: for N-substituted amino alcohols, by reduction of the epime
