161838-99-9

Basic information

• Product Name: dimethyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• Synonyms: 2,6-Dimethyl-3,5-dicarbomethoxy-4-(4-nitrophenyl)-1,4-dihydropyridine; 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-, dimethyl ester; Dimethyl 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)pyridine-3,5-dicarboxylate
• CAS NO: 161838-99-9
• Molecular Formula: C₁₇H₁₈N₂O₆
• Molecular Weight: 346.3346
• Mol File: 161838-99-9.mol
• Article Data: 48

Chemical Properties

• Boiling Point: 493.1°C at 760 mmHg
• Flash Point: 252°C
• Density: 1.271g/cm³
• Vapor Pressure: 7.23E-10mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: dimethyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate(161838-99-9)
• EPA Substance Registry System: dimethyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate(161838-99-9)

Safety Data

• Hazardous Substances Data: 161838-99-9(Hazardous Substances Data)

Upstream product

• 631-61-8 ammonium acetate 
• 555-16-8 4-nitrobenzaldehdye 
• 105-45-3 acetoacetic acid methyl ester 
• 100-13-0 4-nitrostyrene 
• 619-73-8 4-nitrobenzyl chloride 
• 126-81-8 dimedone 
• 624-45-3 levulinic acid methyl ester 
• 105025-71-6 methoxy acetoacetate 
• 67-56-1 methanol 
• 72324-39-1 5-acetyl-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 60-35-5 acetamide 
• 674-82-8 4-methyleneoxetan-2-one 
• 14205-39-1 methyl 3-aminocrotonate 
• 21731-17-9 methyl 3-aminocrotonate 

Downstream Products

• 77233-99-9 2,6-dimethyl-4-(4'-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester 

Relevant articles and documents

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Erbium-Organic Framework as Heterogeneous Lewis Acid Catalysis for Hantzsch Coupling and Tetrahydro-4H-Chromene Synthesis

Abstract: An Erbium-organic framework was prepared by hydrothermal reaction. The prepared framework was characterized by Fourier transform infrared spectroscopy (FT-IR), Scanning electron microscopy (SEM), and X-ray powder diffraction (XRD). The framework has open metal sites at Er(III) centers, thus providing an accessible Lewis acid center for electrophile activation. Accordingly, the synthesized framework was used as Lewis acid heterogeneous catalyst for Hantzsch coupling reaction and tetrahydro-4H-chromene synthesis. The reaction condition has been optimized by variation of the reaction time, temperature, solvent and catalyst concentration. A variety of tetrahydro-4H-chromenes was synthesized and characterized by FT-IR and1H NMR spectroscopy. Er-MOF, as a Lewis acid heterogeneous catalyst, showed excellent selectivity and high yield for these transformations. Graphical Abstract: [Figure not available: see fulltext.]