161852-82-0

Upstream product

• 161665-03-8 (αR,5R,6R)-N-(α-methylbenzyl)-6-difluoromethyl-5-<(tert-butyldimethylsilyl)oxy>-5,6-dihydro-4-pyridone 
• 161665-01-6 (αR,5R,6R)-N-(α-methylbenzyl)-6-difluoromethyl-5-hydroxy-5,6-dihydro-4-pyridone 
• 156978-53-9 (αR,6R)-N-(α-methylbenzyl)-6-difluoromethyl-5,6-dihydro-4-pyridone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 160711-66-0 (αR,5S,6R)-N-(α-methylbenzyl)-6-difluoromethyl-5-<(tert-butyldimethylsilyl)oxy>-5,6-dihydro-4-pyridone 

Relevant academic research and scientific papers

A highly stereocontrolled synthetic approach to 1,6-dideoxy-6,6-difluoroazasugar derivatives

The synthetic utility of (αR, 6R)- or (αR, 6S)-N-(methylbenzyl)-6-difluoromethyl-5,6-dihydro-4-pyridone 2, which was produced from the reaction of 1-methoxy-3-[(trimethylsilyl)oxy]-1,3-butadiene and (αR)- or (αS)-N-(2,2-difluoroethylidene)methylbenzylamin

First Highly Asymmetric Pummerer-type Reaction in Chiral, Non-racemic Acyclic Sulfoxides Induced by O-Silylated Ketene Acetal

Various types of syn- and anti-β-substituted sulfoxides 6b-e, g reacted with ketene tert-butyldimethylsilyl acetal 2 in the presence of a catalytic amount of zinc iodide in acetonitrile to give high yields of the corresponding α-siloxy sulfides 7b-e, g stereoselectively.Similarly, chiral, non-racemic sulfoxides 6a, f, h, i reacted with acetal 2 in acetonitrile to give the chiral, non-racemic α-siloxy sulfides 7a, f, h, i in high yields.