161856-70-8

Basic information

• Product Name: 2,4-Anhydro-D-lyxonic acid Methyl Ester 5-(4-Methylbenzenesulfonate)
• Synonyms: 2,4-Anhydro-D-lyxonic acid Methyl Ester 5-(4-Methylbenzenesulfonate)
• CAS NO: 161856-70-8
• Molecular Weight: 316.332
• Mol File: 161856-70-8.mol

Chemical Properties

• CAS DataBase Reference: 2,4-Anhydro-D-lyxonic acid Methyl Ester 5-(4-Methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Anhydro-D-lyxonic acid Methyl Ester 5-(4-Methylbenzenesulfonate)(161856-70-8)
• EPA Substance Registry System: 2,4-Anhydro-D-lyxonic acid Methyl Ester 5-(4-Methylbenzenesulfonate)(161856-70-8)

Safety Data

• Hazardous Substances Data: 161856-70-8(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 134651-25-5 methyl 2,4-anhydro-D-lyxonate 
• 131139-12-3 methyl 2,4-anhydro-3,5-di-O-benzyl-D-lyxonate 

Downstream Products

• 161856-73-1 (4R,5S,6S)-6-((R)-1-Hydroxy-ethyl)-3-[(2R,3R,4R)-2-methoxycarbonyl-4-(toluene-4-sulfonyloxymethyl)-oxetan-3-ylsulfanyl]-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 161856-72-0 2,4-Anhydro-3-thio-D-arabinonic Acid Methyl Ester 5-(4-Methylbenzenesulfonate) 
• 161856-71-9 (2R,3R,4R)-3-Acetylsulfanyl-4-(toluene-4-sulfonyloxymethyl)-oxetane-2-carboxylic acid methyl ester 

Relevant articles and documents

2-thiosubstituted carbapenems

Carbapenem antibiotic compounds of the general formula: STR1 wherein the moiety STR2 is a 4, 5 or 6 membered mono, di- or tri- substituted oxygen or sulfur containing ring; wherein Z is oxygen, sulfur, sulfoxide and sulfone, pharmaceutical compositions thereof useful for the treatment of bacterial infections, processes for preparing the compounds and new intermediates useful in the process.

Synthesis and structure-activity relationships of some novel oxetane carbapenems

Six disubstituted oxetane carbapenems were synthesized and their antibacterial profile compared with the lead amino methyl THF carbapenem as well as imipenem. The oxetane carbapenems had comparable or less activity against the Gram(-) bacteria and had red