161868-45-7Relevant articles and documents
The preparation of α-substituted, β-hydroxy piperidines and pyrrolidines: The total synthesis of febrifugine
Burgess, Laurence E.,Gross, Elizabeth K. M.,Jurka, Joe
, p. 3255 - 3258 (2007/10/03)
Epoxides generated from cyclic ene carbamates are effective N-acyl iminium ion precursors and allow for the preparation of β-hydroxy, α-substituted piperidines and pyrrolidines. The total synthesis of racemic Febrifugine is also described.