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Usage

Uses

Used in Pharmaceutical Industry:
Ramelteon is used as a sleep aid for the treatment of insomnia. It functions by influencing the body's natural melatonin levels, which are responsible for regulating the sleep-wake cycle. (R)-2-(methoxycarbonyl)-3,3-diphenylpropanoic acid is typically administered orally and has a relatively short half-life, allowing it to effectively induce sleep without causing significant drowsiness the following day.

Upstream product

• 143060-93-9 (R)-β,β-diphenyl-α-alanine hydrochloride 
• 79-22-1 methyl chloroformate 
• 149597-91-1 (2R)-3,3-diphenylalanine 

Relevant academic research and scientific papers

Lysine sulfonamides as novel HIV-protease inhibitors: Nε-Acyl aromatic α-amino acids

A series of lysine sulfonamide analogues bearing Nε-acyl aromatic amino acids were synthesized using an efficient synthetic route. Evaluation of these novel protease inhibitors revealed compounds with high potency against wild-type and multiple-protease inhibitor-resistant HIV viruses.

Pictet-Spengler cyclization of 3,3-diphenylalanine (DIP) (III), synthesis of optically pure 1,2,3,4-tetrahydro-4-phenyl-3-isoquinolinecarboxylic acids, novel α-amino acids for peptides of biological interest

All four isomers of 1,2,3,4-tetrahydro-4-phenyl-3-isoquinolinecarboxylic acid have been synthesized in high optical purity for the synthesis of peptides of biological interest.