16188-30-0 Usage
Uses
Used in Pharmaceutical Industry:
1,3-Thiazol-4-Ylmethylamine is used as a reactant for the preparation of quinazoline antifolate thymidylate synthase inhibitors. It plays a crucial role in the development of these inhibitors by replacing glutamic acid, which contributes to their enhanced efficacy in targeting and inhibiting the enzyme responsible for DNA synthesis and cell proliferation in cancer cells. This application is particularly relevant in the development of novel anticancer drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 16188-30-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,8 and 8 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 16188-30:
(7*1)+(6*6)+(5*1)+(4*8)+(3*8)+(2*3)+(1*0)=110
110 % 10 = 0
So 16188-30-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H6N2S/c5-1-4-2-7-3-6-4/h2-3H,1,5H2
16188-30-0Relevant academic research and scientific papers
CHEMOKINE RECEPTOR BINDING COMPOUNDS
-
Page/Page column 108-109, (2008/06/13)
The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. Thesd compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).
