161887-11-2Relevant academic research and scientific papers
Lipase-catalyzed enantioselective synthesis of optically active mephrobarbital, hexobarbital and febarbamate
Murata,Uchida,Achiwa
, p. 2605 - 2609 (2007/10/02)
Chiral 5,5-disubstituted N-acyloxymethylbarbiturates have been obtained in 40-99% optical yields by lipase-catalyzed hydrolyses of 5,5-disubstituted N,N'-bisacyloxymethylbarbiturates in H2O-saturated diisopropyl ether. These chiral barbiturates
Lipase-catalyzed Enantioselective Hydrolysis of N-Acyloxymethyl Groups in Organic Solvent: Syntheses of Chiral 5,5-Disubstituted 1-Methylbarbiturates
Murata, Masakazu,Achiwa, Kazuo
, p. 6763 - 6766 (2007/10/02)
Chiral 5,5-disubstituted N-acyloxymethylbarbiturates have been obtained in 40-99percent optical yields by lipase-catalyzed hydrolyses of 5,5-disubstituted bisacyloxymethylbarbiturates in H2O-saturated diisopropyl ether.These chiral barbiturates were readi
