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(4-(4-(TERT-BUTYL)PHENYL)(2,5-THIAZOLYL))-1-NAPHTHYLAMINE is a complex organic compound with the molecular formula C27H24N2S. It features a naphthylamine core, which is a derivative of naphthalene with an amine group attached. The compound is characterized by the presence of a 4-(tert-butyl)phenyl group and a 2,5-thiazolyl group, which are attached to the naphthylamine structure. This chemical is known for its potential applications in the synthesis of pharmaceuticals and other specialty chemicals, particularly those involving the development of new drugs or materials with unique properties. The specific arrangement of these functional groups can influence the compound's reactivity, stability, and potential therapeutic effects.

1619-51-8

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1619-51-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1619-51-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,1 and 9 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1619-51:
(6*1)+(5*6)+(4*1)+(3*9)+(2*5)+(1*1)=78
78 % 10 = 8
So 1619-51-8 is a valid CAS Registry Number.

1619-51-8Downstream Products

1619-51-8Relevant academic research and scientific papers

Optimization of 2-aminothiazole derivatives as CCR4 antagonists

Wang, Xuemei,Xu, Feng,Xu, Qingge,Mahmud, Hossen,Houze, Jonathan,Zhu, Liusheng,Akerman, Michelle,Tonn, George,Tang, Liang,McMaster, Brian E.,Dairaghi, Daniel J.,Schall, Thomas J.,Collins, Tassie L.,Medina, Julio C.

, p. 2800 - 2803 (2007/10/03)

A series of 2-aminothiazole-derived antagonists of the CCR4 receptor has been synthesized and their affinity for the receptor evaluated using a [125I]TARC (CCL17) displacement assay. Optimization of these compounds for potency and pharmacokinetic properties led to the discovery of potent, orally bioavailable antagonists.

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