1619-91-6 Usage
General Description
1,1,1,3,3,3-Hexafluoroprop-2-ylamine hydrochloride, also known as HFA-134a hydrochloride, is a chemical compound that is used in the production of pharmaceuticals and agrochemicals. It is a highly reactive and stable compound with a wide range of applications, including as a building block for the synthesis of pharmaceuticals and agrochemicals. It is also used as a key intermediate in the manufacture of various products, such as insecticides and herbicides. Additionally, it is used in the production of refrigerants and fire extinguishing agents due to its high thermal stability and low toxicity. The compound is a colorless liquid that is soluble in water and has a high boiling point, making it suitable for a range of industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1619-91-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,1 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1619-91:
(6*1)+(5*6)+(4*1)+(3*9)+(2*9)+(1*1)=86
86 % 10 = 6
So 1619-91-6 is a valid CAS Registry Number.
1619-91-6Relevant articles and documents
Superiority of Very Weakly Basic Amines as Catalysts for Alpha-Proton Abstraction via Iminium Ion Formation
Roberts, Rex D.,Ferran, Herbert E.,Gula, Michael J.,Spencer, Thomas A.
, p. 7054 - 7058 (1980)
Catalysis of the conversions of beta-ketol 6 and beta-acetoxy ketone 7 to enone 3 via amine-carbonyl condensation has been studied by using eight nontertiary amines having a pKa range from 10.61 to 1.22, including the very weakly basic 3,3,4,4-tetrafluoropyrrolidine (pKa = 4.05) and 1,1,1,3,3,3-hexafluoroisopropylamine (pKa = 1.22).Kinetic terms reflecting rate-determining alpha-proton abstraction via iminium ion formation were identified.Primary kinetic isotope effects were observed when appropriately deuterated 6 and 7 were used.Intermediate eniminium and enimmonium ions 17 were detected.Unlike general-base catalysis, catalysis via iminium ion formation becomes more effective as the base strength of the catalyst decreases.With 1 M hexafluoroisopropylamine as catalyst, formation of 3 from 7 occurs > 104 times via the iminium ion pathway for every time it occurs via direct general-base-catalyzed alpha-proton abstraction.
