16191-17-6

Basic information

• Product Name: 3,6-Dioxabicyclo[3.1.0]hexane-2,4-dione(9CI)
• Synonyms: 3,6-Dioxabicyclo[3.1.0]hexane-2,4-dione(9CI)
• CAS NO: 16191-17-6
• Molecular Formula: C₄H₂O₄
• Molecular Weight: 114.06
• Product Categories: EPOXYDE
• Mol File: 16191-17-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,6-Dioxabicyclo[3.1.0]hexane-2,4-dione(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-Dioxabicyclo[3.1.0]hexane-2,4-dione(9CI)(16191-17-6)
• EPA Substance Registry System: 3,6-Dioxabicyclo[3.1.0]hexane-2,4-dione(9CI)(16191-17-6)

Safety Data

• Hazardous Substances Data: 16191-17-6(Hazardous Substances Data)

Upstream product

• 3272-11-5 2,3-oxiranedicarboxylic acid 
• 16533-72-5 cis-2,3-epoxysuccinic acid 

Downstream Products

• 783255-70-9 (±)-cis-2,3-epoxysuccinamic acid 
• 63544-00-3 methyl (2RS,3SR)-2,3-oxiranedicarboxylate 
• 463-51-4 Ketene 
• 4484-43-9 Formylketen 

Relevant articles and documents

Preparation of dicarboxylate analogues of Cerulenin

We have proposed and synthesized several new structural classes of Cerulenin analogues, which have potential as inhibitors of both fatty acid and polyketide synthase multi-enzyme complexes. These analogues contain cis epoxides bearing flanking carboxylate groups. Our syntheses have been designed to allow access to a wide range of fatty acid and polyketide-like side chains from readily available starting materials in convergent fashion in just four to five steps. In total, ～40 potential analogues have been prepared and characterized, covering all the structural sub-classes proposed, the majority of which constitute novel functional groupings.