161912-34-1

Basic information

• Product Name: 4-methoxyphenyl 4-fluorobenzenesulfonate
• Synonyms: 4-methoxyphenyl 4-fluorobenzenesulfonate
• CAS NO: 161912-34-1
• Molecular Formula: C₁₃H₁₁FO₄S
• Molecular Weight: 282.2874432
• Mol File: 161912-34-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-methoxyphenyl 4-fluorobenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxyphenyl 4-fluorobenzenesulfonate(161912-34-1)
• EPA Substance Registry System: 4-methoxyphenyl 4-fluorobenzenesulfonate(161912-34-1)

Safety Data

• Hazardous Substances Data: 161912-34-1(Hazardous Substances Data)

Upstream product

• 349-88-2 4-Fluorobenzenesulfonyl chloride 
• 150-76-5 4-methoxy-phenol 

Downstream Products

• 94-30-4 ethyl 4-methoxybenzoate 
• 2132-80-1 4,4'-Dimethoxybiphenyl 

Relevant articles and documents

Palladium-catalyzed carbonylation of aryl tosylates and mesylates

A general protocol for the palladium-catalyzed carbonylation of aryl tosylates and mesylates to form esters has been developed using a catalyst system derived from Pd(OAc)2 and the bulky, bidentate dcpp ligand. The system operates under mild conditions: atmospheric CO pressure and temperatures of 80-110 °C. A broad substrate scope has been demonstrated allowing carbonylation of electron-rich, electron-poor, and heterocyclic tosylates and mesylates, and the reaction shows wide functional group tolerance. Copyright

Aryl Mesylates in Metal-Catalyzed Homocoupling and Cross-Coupling Reactions. 1. Functional Symmetrical Biaryls from Phenols via Nickel-Catalyzed Homocoupling of Their Mesylates

Aryl sulfonates including mesylate derived from phenols are converted in high yields to biaryls by homocoupling in the presence of catalytic amounts of zero-valent nickel catalysts generated in situ.This reaction provides the most convenient method for the synthesis of many functional symmetrical biaryls and was applied to the preparation of 2,2'-, 3,3'-, and 4,4'-disubstituted biphenyls and other biaryls.The influence of the electronic and steric effects of substituents attached in the ortho, meta, and para positions of aryl sulfonates and the nature of the sulfonate leaving group on the yield of homocoupled product as well as their influence on the extent of various side reactions were investigated.In addition, the influence of the effects of the polarity and dryness of solvent, halide ion source and concentration, and ratio of catalyst and ligand to aryl sulfonate are discussed.