1619267-34-3Relevant academic research and scientific papers
One-pot synthesis of polysubstituted 3-acylpyrroles by cooperative catalysis
Cui, Hai-Lei,Tanaka, Fujie
, p. 5822 - 5826 (2014/08/05)
One-pot syntheses of polysubstituted 3-acylpyrroles from readily available unsaturated ketones and N-substituted propargylated amines have been developed. An aza-Michael/alkyne carbocyclization cascade, by cooperative catalysis using pyrrolidine and a copper salt, followed by oxidation in situ gave 3-acylpyrroles, which were also transformed further to functionalized, highly substituted 3-acylpyrroles. This journal is the Partner Organisations 2014.
