161957-61-5

Basic information

• Product Name: 3'-Bromo-2'-Fluoroacetophenone
• Synonyms: 3'-Bromo-2'-Fluoroacetophenone;1-(3-Bromo-2-fluoro-phenyl)-ethanone;3'-Bromo-2'-fluoroacetophenone;3-Bromo-2-fluorobenzophenone;1-(3-Bromo-2-fluorophenyl)ethan-1-one;3'-Bromo-2'-fluoroacetophenone 95%
• CAS NO: 161957-61-5
• Molecular Formula: C₈H₆BrFO
• Molecular Weight: 217.0350432
• Product Categories: Adehydes, Acetals & Ketones;Bromine Compounds;Fluorine Compounds
• Mol File: 161957-61-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 252.4±25.0 °C(Predicted)
• Appearance: /Solid
• Density: 1.535±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3'-Bromo-2'-Fluoroacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-Bromo-2'-Fluoroacetophenone(161957-61-5)
• EPA Substance Registry System: 3'-Bromo-2'-Fluoroacetophenone(161957-61-5)

Safety Data

• Hazardous Substances Data: 161957-61-5(Hazardous Substances Data)

Upstream product

• 161957-53-5 1-bromo-2-fluoro-3-(trimethylsilyl)benzene 
• 1072-85-1 o-fluorobromobenzene 
• 680610-73-5 N-methoxy-N-methyl-3-bromo-2-fluorobenzamide 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 881401-77-0 1-(3-Ethyl-2-fluoro-phenyl)-ethanone 
• 1221715-80-5 C₈H₈BrFO 
• 1221715-80-5 C₈H₈BrFO 
• 1313426-12-8 [3-(1,1-difluoroethyl)-2-fluorophenyl]boronic acid 
• 1313426-11-7 2-[3-(1,1-difluoroethyl)-2-fluorophenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1313426-10-6 1-bromo-3-(1,1-difluoroethyl)-2-fluorobenzene 
• 1159511-75-7 7-bromo-3-methyl-1H-indazole 
• 1180016-20-9 (RS)-1-(3-Bromo-2-fluorophenyl)-1-(4-methoxy-3-methylphenyl)ethanol 

Relevant articles and documents

4,5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES

The present invention relates to a compounds of formula I wherein R1, R1′, R2, R3, R4, X, Ar, and m are as defined in the specification and claims and pharmaceutically active acid addition salts thereof. Compounds of the invention have Asp2 (β-secretase, BACE 1 or Memapsin-2) inhibitory activity and are useful for the treatment of diseases characterized by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.

NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION

The present invention relates to compounds which have therapeutic effects against disorders in the central nervous system, and in particular new 4-(ortho, meta-disubstituted phenyl)-1-alkypiperidines and piperazines. (I) wherein R1, R2, R3 and Y are as de

Lithiations directed by carboxylic acid, fluorine and chlorine: The regioselective synthesis of polysubstituted benzoic acids and acetophenones

Lithiation/electrophilic quenching of ortho-lithiated benzoates allows the totally regiocontrolled synthesis of a wide range of 2,3-, 2,3,4-, and 2,3,4,5-polysubstituted benzoic acids and related acetophenones. Elsevier,.