1619986-36-5Relevant academic research and scientific papers
Cu(ii)-Catalyzed asymmetric boron conjugate addition to α,β-unsaturated imines in water
Kitanosono, Taku,Xu, Pengyu,Isshiki, Satoshi,Zhu, Lei,Kobayashi, Shu
, p. 9336 - 9339 (2014/08/05)
Enantioselective conjugate addition of bis(pinacolato)diboron to α,β-unsaturated imines proceeds smoothly in water in the presence of a chiral copper(ii) complex consisting of Cu(OAc)2 and chiral 2,2′-bipyridine. The corresponding β-boryl imines, which were oxidized to β-hydroxy imines, further leading to γ-amino alcohols, were obtained in high yields and high enantioselectivities.
