1619994-69-2 Usage
Description
Bromosporine (1619994-69-2) is a potent pan-Bromodomain (BRD) inhibitor.1?Bromosporine was able to reactivate HIV-1 replication in different latency models.2
Uses
Bromosporine is a broad spectrum inhibitor for bromodomains.
References
1) Picaud?et al.?(2016),?Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia; Sci. Adv.?2?e1600760
2) Pan?et al.?(2017),?The bromodomain and extraterminal domain inhibitor bromosporine synergistically reactivates latent HIV-1 in latently infected cells; Oncotarget?8?94104
Check Digit Verification of cas no
The CAS Registry Mumber 1619994-69-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,1,9,9,9 and 4 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1619994-69:
(9*1)+(8*6)+(7*1)+(6*9)+(5*9)+(4*9)+(3*4)+(2*6)+(1*9)=232
232 % 10 = 2
So 1619994-69-2 is a valid CAS Registry Number.