1620088-66-5Relevant articles and documents
Synthesis and Bioactivity of Benzothiazaphosphepines and Relevant Phosphonates as Antioxidant/Antidiabetic Agents
Abdou, Wafaa M.,Ganoub, Neven A.,Barghash, Reham F.
supporting information, p. 2669 - 2678 (2014/08/18)
An efficient approach to a new series of benzothiazaphosphepines and their derived phosphonates in good yields (64-75%) was reported. The strategy relied on the reactions of the easily available 2-arylmethylene-aminobenzenethiols with different types of Wadsworth-Horner-Emmons (WHE) reagents in dimethylformamide (DMF)/lithium hydride (LiH) solution. All new compounds were bioscreened and showed, in vitro, moderate to good antioxidant and antidiabetic activities.