162011-52-1Relevant academic research and scientific papers
Alkylbenzyl ethers of hydroquinones as monoamine oxidase B inhibitors
Arvanitis, Argyrios G.,Scholfield, Everett L.,Grigoriadis, Dimitri,Heytler, Peter G.,Bowdle, Jack,Chorvat, Robert J.
, p. 115 - 120 (2007/10/03)
A series of alkylbenzylethers of substituted hydroquinone analogs of 4-(3-chlorophenyl methyloxy)-phenoxybutyronitrile I, and alcohol II were synthesized as monoamine oxidase (MAO) inhibitors. Incorporation of electron-withdrawing groups on the hydroquinone afforded compounds with higher levels of activity and selectivity than I or II for MAO B inhibition.
