1620145-05-2Relevant academic research and scientific papers
Highly enantioselective synthesis of bisoxindoles with two vicinal quaternary stereocenters via Lewis base mediated addition of oxindoles to isatin-derived ketimines
Tang, Zhongkai,Shi, Yan,Mao, Haibin,Zhu, Xuebin,Li, Weipeng,Cheng, Yixiang,Zheng, Wen-Hua,Zhu, Chengjian
supporting information, p. 6085 - 6088 (2014/08/05)
A highly efficient asymmetric organocatalytic addition of 3-substituted oxindole to isatin-derived ketimine is reported with excellent stereocontrol (>99:1 dr, >99% ee) under mild conditions. This method provides access to the bisoxindole structure moiety
