1620145-27-8

Upstream product

• 1400564-76-2 3,3-dibenzyl-2-ethyl-(1R,2S,5R)-1′-benzyl-5′-chloro-5-(2-methoxy-2-oxoethyl)-2′-oxospiro[cyclopentane-1,3′-indoline] 2,3,3-tricarboxylate 

Downstream Products

• 1620145-17-6 ethyl 2-(1,1'-dibenzyl-3'-((tert-butoxycarbonyl)amino)-5-chloro-2,2'-dioxo-[3,3'-biindolin]-3-yl)acetate 

Relevant academic research and scientific papers

Enantioselective direct Mannich reactions of 3-substituted oxindoles catalyzed by chiral phosphine via dual-reagent catalysis

A combination of an amino acid-derived chiral phosphine catalyst and methyl acrylate to catalyze the direct Mannich reaction of 3-substituted oxindoles and imines has been reported to afford 3-tetrasubstituted oxindole derivatives which are key structures