1620159-63-8Relevant academic research and scientific papers
Synthesis of functionalized N-triazolyl maleimides
Stefani, Hélio A.,Ferreira, Fernando P.,Ali, Bakhat,Pimenta, Daniel C.
, p. 4355 - 4358 (2014/07/22)
An easy and mild two-step one-pot reaction allowed the synthesis of functionalized N-triazolyl maleimide. Next, the addition of propargyl alcohol and propargyl amine to the N-acyliminium ion mediated by Lewis acid, In(OTf)3, allowed the introduction of a second 1,2,3-triazol ring at position 5 of the amide. The products in both reactions were achieved in moderate to good yields.
