162019-09-2

Upstream product

• 162019-08-1 2,3,4,6-tetrakis-O-(phenylmethyl)-D-xylo-hexos-5-ulose 1-(O-methyloxime) 
• 59531-24-7 2,3,4,6-tetra-O-benzyl-D-glucopyranoside 
• 162119-07-5 (2S,3R,4R,5R)-2,3,4,6-Tetrakis-benzyloxy-5-hydroxy-hexanal O-methyl-oxime 
• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 

Downstream Products

• 162019-10-5 [1R-(1α,2α,3β,4α,5β)]-2-amino-3,4,5-tris(phenylmethoxy)-1-[(phenylmethoxy)methyl]cyclopentanol 

Relevant academic research and scientific papers

Radical cyclization in heterocycle synthesis. Part 9: A novel synthesis of aminocyclitols and related compounds via stannyl radical cyclization of oxime ethers derived from sugars

Stannyl radical addition-cyclization of oxime ethers derived from D-glucose, D-galactose, and D-xylose proceeded smoothly to afford alkoxyamino alcohols which were effectively converted into two types of glycosidase inhibitors or its candidates such as aminocyclitols, 1-deoxynojirimycin, and 1-deoxygalactostatin via reductive ring-expansion of trans alkoxyamino alcohols. (C) 2000 Elsevier Science Ltd.

A Novel and Concise Synthesis of Aminocyclopentitols and 1-Deoxynojirimycin via Radical Cyclization of Oxime Ethers

Tributyltin hydride-induced radical cyclization of the oxime ether 3 derived from D-glucose proceeded smoothly to give two amino alcohols 4 and 5 which were converted into two aminocyclopentitol pentaacetates 8 and 12 and 1-deoxynojirimycin known as glyco