162019-92-3

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 162019-87-6 (2S,3R,4Z)-2-azido-1-benzoyloxy-4-octadecen-3-ol 
• 162019-89-8 (2S,3R,4Z)-3-(tert-butyldimethylsilyloxy)-2-(2,4-dinitrophenyl)amino-4-octadecen-1-ol 
• 70-34-8 2,4-Dinitrofluorobenzene 
• 162019-90-1 (2S,3R,4Z)-3-(tert-butyldimethylsilyloxy)-2-(2,4-dinitrophenyl)amino-1-iodo-4-octadecene 
• 162019-88-7 (2S,3R,4Z)-2-azido-3-(tert-butyldimethylsilyloxy)-4-octadecen-1-ol 
• 104826-37-1 (2S,3R,4Z)-2-azido-octadec-4-ene-1,3-diol 

Downstream Products

• 162119-29-1 (2S,3R,4Z)-3-tert-butyldimethylsilyloxy-2-(2,4-dinitrophenyl)-amino-1-(3,4-O-isopropylidene-5a-carba-β-D-galactopyranosylamino)-4-octadecene 
• 162119-27-9 (2S,3R,4Z)-1-(4,6-O-benzylidene-5a-carba-β-D-glucopyranosylamino)-3-(tert-butyldimethylsilyloxy)-2-(2,4-dinitrophenyl)amino-4-octadecene 
• 162428-06-0 (2S,3R,4Z)-1-<6-O-tert-butyldimethylsilyl-2,3-di-O-methoxymethyl-5a-carba-α-L-arabino-hex-5(5a)-enopyranosylamino>-3-tert-butyldimethylsilyloxy-2-(2,4-dinitrophenyl)amino-4-octadecene 
• 162428-03-7 (2S,3R,4Z)-1-<5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamino>-2-(2,4-dinitrophenyl)amino-4-octadecen-3-ol 
• 162119-28-0 (2S,3R,4Z)-1-(5a-carba-β-D-glucopyranosylamino)-2-(2,4-dinitrophenyl)amino-4-octadecen-3-ol 
• 162119-31-5 (2S,3R,4Z)-1-(5a-carba-β-D-galactopyranosylamino)-2-(2,4-dinitrophenyl)amino-4-octadecen-3-ol 
• 162428-08-2 (2S,3R,4Z)-1-<5a-carba-α-L-arabino-hex-5(5a)-enopyranosylamino>-2-(2,4-dinitrophenyl)amino-4-octadecen-3-ol 
• 157750-06-6 (2S,3R,4Z)-3-tert-butyldimethylsilyloxy-1-<2,3:4,6-di-O-isopropylidene-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamino>-2-(2,4-dinitrophenyl)amino-4-octadecene 

Relevant academic research and scientific papers

Synthesis of 5a-Carba-&β-D-glycosylceramide Analogs Linked by Imino, Ether and Sulfide Bridges

Carbocyclic analogs of glycoceramides, (2S,3R,4E)-1-(5a-carba-β-D-glycopyranosyl)-2-(hexadecanoylamino)-4-octadecen-3-ols E-3 - E-6, linked by imino, ether and sulfide bridges, were synthesized by coupling of aziridines, as the sphingosine precursors, wit

Synthesis of glucosylceramide analogues. Imino-linked 5a-carbaglycosylceramides, potent and specific glucocerebrosidase inhibitors

Imino-linked carbocyclic analogues (E)- and (Z)-2 of glucosylceramide 1 have been synthesized and shown to be potent and specific inhibitors against glucocerebrosidase.