1620286-05-6

Basic information

• Product Name: tert-butyl N-[(1Z)-{[(2R,3S,4S,4aS,8aS)-4-[(3,5-dihydroxyphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-yl]amino}({[(tert-butoxy)carbonyl]imino})methyl]carbamate
• Synonyms: tert-butyl N-[(1Z)-{[(2R,3S,4S,4aS,8aS)-4-[(3,5-dihydroxyphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-yl]amino}({[(tert-butoxy)carbonyl]imino})methyl]carbamate
• CAS NO: 1620286-05-6
• Molecular Weight: 587.757
• Mol File: 1620286-05-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl N-[(1Z)-{[(2R,3S,4S,4aS,8aS)-4-[(3,5-dihydroxyphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-yl]amino}({[(tert-butoxy)carbonyl]imino})methyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl N-[(1Z)-{[(2R,3S,4S,4aS,8aS)-4-[(3,5-dihydroxyphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-yl]amino}({[(tert-butoxy)carbonyl]imino})methyl]carbamate(1620286-05-6)
• EPA Substance Registry System: tert-butyl N-[(1Z)-{[(2R,3S,4S,4aS,8aS)-4-[(3,5-dihydroxyphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-yl]amino}({[(tert-butoxy)carbonyl]imino})methyl]carbamate(1620286-05-6)

Safety Data

• Hazardous Substances Data: 1620286-05-6(Hazardous Substances Data)

Upstream product

• 52618-00-5 (1R,2R,4aS,8aS)-(+)-2-hydroxy-1,2,3,4,4a,5,6,7,8,8a-decahydro-2,5,5,8a-tetramethyl-naphthalen-1-aldehyde 
• 20469-65-2 1-bromo-3,5-dimethoxybenzene 
• 1619983-13-9 5-{[(1S,2S,3R,4aS,8aS)-3-amino-2,5,5,8a-tetramethyldecahydronaphthalen-1-yl]carbonyl}benzene-1,3-diol 
• 152120-54-2 N,N'-bis( tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine 
• 1619983-12-8 (2R,4aS,8aS)-4-[(3,5-dimethoxyphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-amine 
• 1619983-11-7 (2R,4aS,8aS)-4-[(3,5-dimethoxyphenyl)carbonyl]-N-[(4-methoxyphenyl)methyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-amine 
• 1619983-10-6 (3R,4S,4aS,8aS)-4-[(3,5-dimethoxyphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-one 
• 1619983-09-3 (2R,3R,4S,4aS,8aS)-4-[(3,5-dimethoxyphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-ol 
• 1619983-08-2 [(1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](3,5-dimethoxyphenyl)methanone 
• 1619983-07-1 (1R,2R,4aS,8aS)-1-[(3,5-dimethoxyphenyl)carbonyl]-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol 

Downstream Products

• 1619983-80-0 1-[(2R,4aS,8aS)-4-[(3,5-dihydroxyphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-yl]guanidine 

Relevant articles and documents

SHIP1 MODULATORS AND METHODS RELATED THERETO

Compounds of formula (I): [Formula should be inserted here]; where [Formula should be inserted here], n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed compounds have activity as SHIP1 modulators, and thus may be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. Compositions comprising a compound of formula (I) in combination with a pharmaceutically acceptable carrier or diluent are also disclosed, as are methods of SHIP1 modulation by administration of such compounds to an animal in need thereof.