16204-05-0 Usage
Molecular structure
The compound contains a 1H-Indene core structure with a carboxylic acid group (-COOH) at position 3, a methoxy group (-OCH3) at position 5, a methyl group (-CH3) at position 2, and a substituted phenyl ring (p-tolyl) at position 1.
Plant hormone derivative
The compound is a derivative of 1H-indene-3-acetic acid, a plant hormone that plays a role in the growth and development of plants.
Anti-inflammatory and analgesic activities
The compound has been studied for its potential anti-inflammatory and analgesic activities, making it of interest in the pharmaceutical industry.
Chemical reactivity
The presence of the methoxy and methyl groups, as well as the substituted phenyl ring, can affect the compound's chemical reactivity and make it suitable for use in the production of dyes, pigments, and other industrial products.
Molecular weight
270.33 g/mol
Physical state
Solid
Appearance
White or off-white crystalline solid
Solubility
Slightly soluble in water, soluble in organic solvents such as ethanol, methanol, and chloroform.
Melting point
160-162°C.
Check Digit Verification of cas no
The CAS Registry Mumber 16204-05-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,0 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 16204-05:
(7*1)+(6*6)+(5*2)+(4*0)+(3*4)+(2*0)+(1*5)=70
70 % 10 = 0
So 16204-05-0 is a valid CAS Registry Number.
16204-05-0Relevant articles and documents
Identification of Potent Ras Signaling Inhibitors by Pathway-Selective Phenotype-Based Screening
Mueller, Oliver,Gourzoulidou, Eleni,Carpintero, Mercedes,Karaguni, Ioanna-Maria,Langerak, Anette,Herrmann, Christian,Moeroey, Tarik,Klein-Hitpass, Ludger,Waldmann, Herbert
, p. 450 - 454 (2004)
Blocking the path to cancer: Application of efficient strategy for a phenotype-based screening of compound libraries to a library of sulindac-derived compounds (see scheme) yielded new inhibitors of the tumor-relevant Ras signal transduction pathway with high fidelity (as shown by microscopy). The results underline the advantage of using biologically prevalidated compound classes in chemical biology research.
