16204-16-3Relevant articles and documents
Iodine(III)-mediated ring contraction reactions: Synthesis of oxygen-And nitrogen-substituted indanes
Ahmad, Anees,Silva, Luiz F.
, p. 1820 - 1831 (2016/10/18)
The synthesis of oxygen-And nitrogen-substituted indanes was successfully performed by iodine(III)-mediated ring contraction of 1,2-dihydronaphthalenes. Acetoxy and benzoyloxy alkenes afforded indanes in 60-71percent yield, irrespective of their position on aromatic ring. Similarly, the nitrogen containing substrates protected with 9-fluorenylmethyloxycarbonyl (Fmoc) and benzoyl (Bz) groups smoothly undergoes ring contraction giving indanes in 64-77percent yield. The tosyl-protected substrate resulted only in addition products.