16204-38-9Relevant academic research and scientific papers
Synthesis and in vitro antimalarial activity of tetraoxane-amine/amide conjugates
Kumar, Nitin,Khan, Shabana I.,Atheaya, Himanshu,Mamgain, Ritu,Rawat, Diwan S.
experimental part, p. 2816 - 2827 (2011/07/08)
A series of tetraoxanes, tetraoxane-amine and tetraoxane-amide conjugates have been synthesized and screened for in vitro antimalarial activity against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum. Most of the conjugate
Iodine-catalyzed one-pot synthesis and antimalarial activity evaluation of symmetrically and asymmetrically substituted 3,6-diphenyl[1,2,4,5]tetraoxanes
Kumar, Nitin,Khan, Shabana I.,Sharma, Mukul,Atheaya, Himanshu,Rawat, Diwan S.
scheme or table, p. 1675 - 1677 (2009/10/15)
A novel iodine-catalyzed one-pot synthesis of symmetrically and asymmetrically substituted 3,6-diphenyl-[1,2,4,5]tetraoxanes is described. The synthetic protocol is general with substituted benzaldehydes and proceeds well under acidic conditions. Total 17
Synthesis, thermal stability, antimalarial activity of symmetrically and asymmetrically substituted tetraoxanes
Atheaya, Himanshu,Khan, Shabana I.,Mamgain, Ritu,Rawat, Diwan S.
, p. 1446 - 1449 (2008/12/21)
Symmetrically and asymmetrically substituted 1,2,4,5-tetraoxanes were synthesized by the oxidative system H2O2/TFE in presence of MeReO3 as a catalyst. All of the synthesized compounds were characterized spectroscopically,
Synthesis and X-Ray Analysis of 2,3,5,6,11-Pentaoxabicycloundecanes
Miura, Masahiro,Ikegami, Akio,Nojima, Masatomo,Kusabayashi, Shigekazu,McCullough, Kevin J.,Walkinshaw, Malcolm D.
, p. 1657 - 1664 (2007/10/02)
The reactions of bicyclic ozonides and aldehyde- or ketone-derived peroxides, performed or generated in situ, in the presence of chlorosulphonic acid afford the corresponding 2,3,5,6,11-pentaoxabicycloundecanes.In addition, 1,2,4,5-tetraoxans are often isolated from the product mixture.Mechanisms are proposed to account for the observed peroxidic products.An X-ray analysis of the crystalline product (4b) confirms the general structure and reveals that it is solely the exo-isomer.
