1620458-09-4

Basic information

• Product Name: Angiontensin(1-7)
• Synonyms: Angiontensin(1-7);AZD0914;(2R,4S,4aS)-11-Fluoro-1,2,4,4a-tetrahydro-2,4-dimethyl-8-[(4S)-4-methyl-2-oxo-3-oxazolidinyl]spiro[isoxazolo[4,5-g][1,4]oxazino[4,3-a]quinoline-5(6H),5'(2'H)-pyrimidine]-2',4',6'(1'H,3'H)-trione
• CAS NO: 1620458-09-4
• Molecular Formula: C22H22FN5O7
• Molecular Weight: 487.44
• Mol File: 1620458-09-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.61±0.1 g/cm3(Predicted)
• PKA: 10.44±0.60(Predicted)
• CAS DataBase Reference: Angiontensin(1-7)(CAS DataBase Reference)
• NIST Chemistry Reference: Angiontensin(1-7)(1620458-09-4)
• EPA Substance Registry System: Angiontensin(1-7)(1620458-09-4)

Safety Data

• Hazardous Substances Data: 1620458-09-4(Hazardous Substances Data)

Usage

Uses

Zoliflodacin, is a spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor, and has in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus.

Upstream product

• 171753-74-5 (2R,6R)-2,6-dimethylmorpholine 
• 67-52-7 BARBITURIC ACID 
• 161793-17-5 2,3,4-trifluorobenzaldehyde 
• 141-91-3 cis-2,6-dimethylmorpholine 

Relevant articles and documents

FUSED, SPIROCYCLIC HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS

Disclosed are methods for treating various bacterial infections with (2R,4S,4aS)-11-fluoro-2,4-dimethyl-8-[(4S)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a][1,2]oxazolo[4,5-g]quinoline-5,5'-pyrimidine]-2',4',6' (1'H,3'H)-trione, or a pharmaceutically acceptable salt thereof.

COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS

Compounds of formula (I), pharmaceutically acceptable salts thereof, and uses of the compounds of formula (I) for treating bacterial infections are disclosed.