162046-59-5

Basic information

• Product Name: 2-CHLORO-4-(CHLOROMETHYL)-6-METHYLPYRIDINE
• Synonyms: 2-CHLORO-4-(CHLOROMETHYL)-6-METHYLPYRIDINE
• CAS NO: 162046-59-5
• Molecular Formula: C7H7Cl2N
• Molecular Weight: 176.04318
• Mol File: 162046-59-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 258.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.270±0.06 g/cm3(Predicted)
• PKA: 1.09±0.10(Predicted)
• CAS DataBase Reference: 2-CHLORO-4-(CHLOROMETHYL)-6-METHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-(CHLOROMETHYL)-6-METHYLPYRIDINE(162046-59-5)
• EPA Substance Registry System: 2-CHLORO-4-(CHLOROMETHYL)-6-METHYLPYRIDINE(162046-59-5)

Safety Data

• Hazardous Substances Data: 162046-59-5(Hazardous Substances Data)

Upstream product

• 152815-18-4 (2-chloro-6-methyl-pyridin-4-yl)-methanol 
• 25462-85-5 2-chloro-6-methylpyridine-4-carboxylic acid 

Downstream Products

• 1610358-63-8 (rac)-5-bromo-N-[5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl]-6-methyl-4-[(S-methylsulfonimidoyl)methyl]pyridin-2-amine 
• 1610358-61-6 (rac)-5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{6-methyl-4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine 
• 1610359-07-3 (rac)-N-{[(3-bromo-6-{[5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl]amino}-2-methylpyridin-4-yl)methyl](methyl)-λ⁴-sulfanylidene}-2,2,2-trifluoroacetamide 
• 1610359-35-7 (rac)-2,2,2-trifluoro-N-{[(2-{[5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl]amino}-6-methylpyridin-4-yl)methyl](methyl)-λ⁴-sulfanylidene}acetamide 
• 1602486-09-8 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-N-{6-methyl-4-[(methylsulfanyl)methyl]pyridin-2-yl}pyridin-2-amine 
• 1610462-76-4 (R)-6-(4-fluoro-2-methoxyphenyl)-N-{6-methyl-4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyrimidin-4-amine 
• 1610462-77-5 (S)-6-(4-fluoro-2-methoxyphenyl)-N-{6-methyl-4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyrimidin-4-amine 
• 1610462-75-3 (rac)-6-(4-fluoro-2-methoxyphenyl)-N-{6-methyl-4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl}pyrimidin-4-amine 
• 1610462-86-6 (rac)-2,2,2-trifluoro-N-{[(2-{[6-(4-fluoro-2-methoxyphenyl)pyrimidin-4-yl]amino}-6-methylpyridin-4-yl)methyl](methyl)-λ⁴-sulfanylidene}acetamide 
• 1603922-87-7 6-(4-fluoro-2-methoxyphenyl)-N-{6-methyl-4-[(methylsulfonyl)methyl]pyridin-2-yl}pyrimidin-4-amine 
• 1603923-09-6 C₁₉H₁₉FN₄OS 

Relevant articles and documents

CGRP RECEPTOR ANTAGONISTS

The present invention provides a compound of Formula II: (II) or a pharmaceutically acceptable salt thereof.

N-(PYRIDIN-2-YL)PYRIMIDIN-4-AMINE DERIVATIVES CONTAINING A SULFONE GROUP

The present invention relates to N-(pyridin-2-yl)pyrimidin-4-amine derivatives containing a sulfone group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorder

5-FLUORO-N-(PYRIDIN-2-YL)PYRIDIN-2-AMINE DERIVATIVES CONTAINING A SULFOXIMINE GROUP

The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).